The project “Sense with Body'' is an art therapy center design that addresses the multisensory integration of autistic children and comforts them when they are being exposed to an unfamiliar environment. Autistic children suffer from difficulties when integrating their senses, interacting and communicating with others. They experience sensory in different ways. In order to resolve the conflict of sensory and issue of autistic behavior, the program will be an art therapy which is considered as a method that can improve imaging and group working, and stimulate motor skills. The most difficult part of this project is to find a proposal that can simultaneously satisfy the demands of different groups of autistic children. To solve this problem, I have done detailed research about the autism. Based on some common behaviors and symptoms, the autistic children can generally be characterized in two categories: hyposensitive autism and hypersensitive autism. The way hyposensitive group perceive the sense of tactility, auditory, and vision are diminished and it’s hard for them to focus continuously. Hypersensitive group is very sensitive to saturated colors, different textures, and certain scenes. Therefore, in my designed therapy rooms, hypersensitive group will have less material variation and muted color while the hyposensitive group will have more material textures and saturated color.